Experience: 5-8 years post qualification
Education: M. Pharm or M.V. Sc. (Pharmacology & Toxicology)
Role Accountabilities:
- Conduct of pharmacokinetic studies in rodents.
- Documenting the lab notebooks online and compound management.
- Ability to adapt to the dynamic team environment.
- Possess the knowledge and exposure to environment, health, and safety (EHS) practices
- Follow environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab/plant safety
- Ensure environment, health, and safety (EHS) measures are imparted via training and adhered within the team.
Skills and Capabilities:
- Well versed with surgical procedures like cannulation of jugular, femoral, portal vein in rats. Chronic bile duct cannulations in rat and various animal models used for in vivo pharmacokinetics studies.
- Collection of different vital organs during tissue distribution studies in rodents
- Pharmacokinetic data analysis using Phoenix WinNonlin and other data analysis tool.
- Collection of various biological fluids like cerebrospinal fluid, bile, urine, synovial fluid lavage during PK and tissue distribution studies in rodents.
- Should have preliminary understanding about formulations to be used for pharmacokinetics, efficacy and toxicity studies.
- Knowledge about regulatory guidelines followed for drug metabolism and pharmacokinetics is desirable.
Job Purpose
- Conduct of in vivo pharmacokinetics study in rodents
Key Responsibilities:
- Conduct of pharmacokinetic studies in rodents.
- Preparation of study protocols, reports for IND/ NDA submissions.
- Documenting the lab notebooks online and compound management.
- Ability to adapt to the dynamic team environment.
- Possess the knowledge and exposure to environment, health, and safety (EHS) practices
- Follow environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab/plant safety
- Ensure environment, health, and safety (EHS) measures are imparted via training and adhered within the team
Technical/functional Skills:
- Well versed with surgical procedures like cannulation of jugular, femoral, portal vein in rats. Chronic bile duct cannulations in rat and various animal models used for in vivo pharmacokinetics studies.
- Collection of different vital organs during tissue distribution studies in rodents
- Pharmacokinetic data analysis using Phoenix WinNonlin and other data analysis tool.
- Collection of various biological fluids like cerebrospinal fluid, bile, urine, synovial fluid lavage during PK and tissue distribution studies in rodents.
- Sound understanding about ADME assays and their correlations with pharmacokinetic parameters
- Should have preliminary understanding about formulations to be used for pharmacokinetics, efficacy and toxicity studies.
- Knowledge about regulatory guidelines followed for drug metabolism and pharmacokinetics is desirable.
Behavioral Skills:
- Candidate need to be a team player.
- Ready to take new challenges, committed to work and timelines
- Should have learning attitude, enthusiastic and hard working
- Good in communication skills
Apply: https://careers.syngeneintl.com/job/Bangalore-In-vivo-PK-scientist/1251762700/